A serological study of tuberculosis patients for Dirofilaria immitis infection in Malaysia

Stephen Ambu¹, Yit Yoke Heong¹, Kuppusamy I², Khairul Anuar A³ and Lokman Hakim¹

1. Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Malaysia

2.  Institute of Respiratory Medicine, Jalan Tun Abdul Razak, 50590 Kuala Lumpur, Malaysia

3. Faculty of Medicine. University of Malaya, 50603 Kuala Lumpur, Malaysia.

Correspondence: Dr Stephen Ambu; e-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.

CITATION: Stephen Ambu, Yit Yoke Heong, Kuppusamy I, Khairul Anuar A, Lokman Hakim. A serological study of tuberculosis patients for Dirofilaria immitis infection in Malaysia. International Medical Research Journal. 2002;6(1):27–32. 

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ABSTRACT

In this study we investigated evidence of Dirofilaria immitis infection among TB patients admitted to the Medical Respiratory Institute of the Ministry of Health Malaysia. Three hundred blood sera samples were analysed using enzyme-linked immunosorbent assay and Western Blot methodology. Six positive cases were detected based on antibodies reactive to polypeptides of D. immitis at MW 212, 116 and 77 kDa using Western Blot analysis.

KEYWORDS: Dirofilariasis, human, diagnosis